Could a peptide gel make early cavities disappear?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age \>10 years and \<18 years. 2. Presence of at least 2 active enamel carious white spot lesions on a smooth tooth surface (labial/buccal surfaces of permanent teeth) based on International Caries Detection (ICDAS II) and Assessment System -Lesion Activity Assessment (ICDAS-LAA), and Lesion Activity Assessment (LAA criteria). 3. Tooth eligible for treatment: 1. Vital pulp, 2. no loss of hard dental tissues within the investigated lesion (ICDAS II) code 1 or 2 , LAA code 1, ICDAS-LAA\>7; 3. QLF score parameters consistent with demineralization without loss of tissue continuity- code 1 or 2), 4. no history of trauma to the tooth. 4. Systemically healthy patient. 5. No contraindications to the use of fluoride preparations. 6. No fixed orthodontic appliance. 7. Written consent for participation in the study signed by the legal guardian, or by the legal guardian and the patient. Exclusion Criteria: 1. Systemic diseases or chronic medication use due to chronic conditions. 2. Viral/bacterial illness on the day of the visit, e.g., herpetic stomatitis, influenza, tonsillitis (temporary restriction). 3. Pregnancy or breastfeeding. 4. Allergy to any component of the SAP P11-4 preparation or the fluoride varnish. 5. Professional fluoride prophylaxis performed \<3 months ago. 6. Presence of cavitation (loss of hard tissues) in the treated tooth - ICDAS II code ≥3, ICDAS-LAA\<7, LAA code 0, 2-9. 7. Carious WSL previously treated with the Icon resin infiltrant (methacrylate resin). 8. Developmental enamel defects. 9. Patient undergoing orthodontic treatment with fixed appliances. 10. Inability to ensure regular follow-up visits. 11. Lack of cooperation from the guardian or the patient. 12. Refusal to participate in the study and/or absence of written consent.