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New gum graft aims to save jawbone after tooth extraction

NCT ID NCT06783660

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new material called PeptiCol EZgraft, placed in the tooth socket right after extraction, to help preserve the jawbone for future dental implants. About 114 adults aged 19-75 with healthy gums and at least half the bone wall intact will be randomly assigned to get either the new graft or a standard one (Regenomer). The main goal is to see which better maintains bone width and shape over 4 months, while also checking for side effects like pain or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 114 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Feb 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adults aged 19 to 75 years. 2. Systemically healthy or with mild systemic disease, classified as ASA I or II. 3. Planning to place implants in the maxilla or mandible after extraction, or having such plans for the future. If there are multiple extraction sockets, only one socket will be included in the trial, and other areas will follow spontaneous healing or treatment plans. 4. The extraction socket area must have more than 50% of the alveolar bone wall remaining. 5. Willing to maintain good oral hygiene during the clinical trial. 6. Voluntarily decided to participate in the trial and signed the informed consent form. 7. Willing to participate for the entire duration of the clinical trial and comply with trial procedures. Exclusion Criteria: 1. Extensive alveolar bone absorption observed in the extraction socket area. 2. Severe periodontal disease or acute periodontal abscess. 3. Poor oral hygiene. 4. History of bone grafts or implants in the area of the medical device application. 5. Mucosal diseases due to autoimmune disorders. 6. History of hypersensitivity to collagen preparations. 7. Smoking more than 10 cigarettes per day. 8. Alcohol or drug addiction. \*The alcohol addiction screening will be conducted using AUDIT-K. 9. Use of drugs affecting bone formation within 2 weeks prior to screening (e.g., steroids, bisphosphonates). 10. Use of oral or injectable rheumatic medications, including immunosuppressants, within 2 weeks prior to screening. 11. History of or current use of oral or injectable bisphosphonates for osteoporosis for more than 12 weeks. 12. Uncontrolled bleeding disorders or use of medications affecting blood coagulation. 13. Uncontrolled diabetes or hypertension. 14. Clinically significant cardiovascular, gastrointestinal, respiratory, endocrine, or central nervous system diseases observed at screening. 15. Immune disorders including acquired immunodeficiency syndrome. 16. Pregnant or breastfeeding women 17. During the clinical trial period, female and male participants who are of childbearing potential must agree to use appropriate contraception from the date of signing the informed consent form until the end of the clinical trial (16 weeks post-procedure). If a female participant becomes pregnant during the trial period, her participation will be discontinued.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • Seoul National University Dental Hospital

    RECRUITING

    Korea, Seoul, 03080, South Korea

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