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Gum fluid test could spot hidden inflammation in denture patients

NCT ID NCT07271563

Diagnosis Sponsor: Jagiellonian University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether measuring a substance called pentraxin in the fluid around teeth can help detect early gum disease in people who have fixed dentures. Researchers studied 90 patients to see if pentraxin levels could reveal inflammation that isn't visible during a regular dental exam. The goal is to improve planning for dental treatments and catch problems sooner.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this diagnostic test could help dentists detect early gum inflammation around denture-supporting teeth before it becomes visible.
What could go wrong
This is a small, completed observational study. The test is not yet proven to improve patient outcomes and may not be adopted in routine practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

90 people

The number who actually took part.

Started

Mar 2023

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study material consist of 90 patients, of both sexes, aged between 35-48 years, who report for prosthetic treatment with fixed dentures to the University Dental Clinic at the Institute of Dentistry in Krakow, in the period: March 2023- August 2024.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * appropriate age range of patients, indication for the use of fixed dentures, no signs of gingivitis in the clinical examination Exclusion Criteria: * any autoimmune disease or other systemic disease which could alter the course of periodontal disease, the desire to withdraw from participation in the research and the occurrence of general and local diseases

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Conditions

The condition(s) this trial relates to.

periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontal disease Periodontal diseases Prosthodontics

Contacts and locations

Locations

  • Dental Institute

    Krakow, 31-155, Poland

More trials for these conditions

Other studies related to the condition(s) this trial covers.