Could a simple additive make hip surgery recovery less painful for seniors?
NCT ID NCT07330999
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares three versions of a nerve block (PENG block) for pain relief in 120 adults aged 65 and older having hip surgery. One group gets the standard block, while two others get an added medication (dexamethasone or dexmedetomidine) to see if pain relief lasts longer. The goal is to reduce pain and the need for strong painkillers after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 65 years or older * Scheduled for elective or emergency hip surgery (e.g., hip fracture fixation or hip arthroplasty) * ASA physical status I-III * Planned use of a PENG block as part of perioperative analgesia * Ability to communicate pain intensity using the NRS scale * Written informed consent obtained from the patient or legal representative Exclusion Criteria: * Refusal or inability to provide informed consent * Known allergy, intolerance, or contraindication to any of the study medications: ropivacaine, dexamethasone, dexmedetomidine * Pre-existing neurological deficit or neuropathy in the affected limb * Coagulopathy or laboratory abnormality that contraindicates regional anesthesia: INR \>1.5, or platelet count \<100,000/µL, or therapeutic anticoagulation that cannot be safely paused * Infection at or near the needle insertion site * Severe hepatic or renal impairment * Chronic opioid therapy (\>30 days of daily opioids before surgery) * Cognitive impairment or delirium that prevents reliable pain assessment * BMI \>40 kg/m² (due to potential technical difficulty and reduced accuracy of ultrasound guidance) * Previous regional block affecting the target area for the current surgery * Pregnancy or breastfeeding * Participation in another interventional clinical trial within 30 days
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Poznan University of Medical Sciences
RECRUITINGPoznan, 62-701, Poland
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Other studies related to the condition(s) this trial covers.
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- Could a 2-Hour online class before hip surgery boost recovery?