Which pain relief helps you recover faster after hip surgery?
NCT ID NCT07803133
First seen Sep 03, 2026 · Last updated Sep 10, 2026 · Updated 3 times
Summary
This trial tests two ways to manage pain after hip replacement surgery: a nerve block near the hip joint (PENG block) and a small dose of morphine given with spinal anesthesia. Adults scheduled for elective hip replacement will be randomly assigned to one of the two methods. Researchers will measure quality of recovery 24 hours after surgery using a questionnaire, and also track pain, opioid use, movement, and side effects. The goal is to see if one approach leads to a smoother, more comfortable recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Pericapsular nerve group (PENG) block with bupivacaine, compared to intrathecal morphine
- What this could lead to
- If one method works better, it could point to a standard way to manage pain after hip replacement, helping people recover faster and with fewer side effects.
- What could go wrong
- This is a single trial with 90 participants, so results may not apply to everyone. Both methods carry risks like allergic reactions or nerve damage, and the trial has not yet reported outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18-85 years * American Society of Anesthesiologists (ASA) physical status I-III * Scheduled for elective primary unilateral total hip arthroplasty * Planned spinal anesthesia * Ability to understand and complete the Quality of Recovery-15 (QoR-15) questionnaire and Numeric Rating Scale (NRS) pain assessments * Provision of written informed consent Exclusion Criteria: * Contraindication to spinal anesthesia or PENG block * Known allergy or hypersensitivity to local anesthetics or morphine * Coagulation disorder * Therapeutic anticoagulant use * Infection at the planned injection site * Chronic opioid use * History of substance abuse * Severe cognitive impairment that prevents reliable completion of study assessments * Advanced hepatic or renal failure * ASA physical status IV or higher * Revision total hip arthroplasty * Surgery for pathological fracture or tumor * Pregnancy * Requirement for general anesthesia * Refusal to participate in the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Erzincan Binali Yildirim University Mengucek Gazi Training and Research Hospital
Erzincan, Erzincan, 06170, Turkey (Türkiye)
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