Can a targeted nerve block tame Post-Surgery pain and curb opioid use?
NCT ID NCT07765095
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This trial tests whether a pericapsular nerve group (PENG) block, a type of regional nerve block, can reduce pain after surgery to repair a fractured hip socket (acetabulum). Adults undergoing this surgery will be randomly assigned to receive either the PENG block or no block, alongside standard pain medications. Researchers will compare pain scores, opioid use, and side effects to see if the block offers better pain control and safety.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Pericapsular nerve group (PENG) block, a regional nerve block procedure
- What this could lead to
- If effective, this nerve block could become a standard way to ease pain and cut opioid use after hip socket fracture surgery.
- What could go wrong
- This is a small, early-stage trial, and the block may not provide meaningful pain relief or reduce opioid needs. There is also a risk of side effects or complications from the procedure itself.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient age 18 years or older * Acetabular Fracture amenable to surgery through the Kocher-Langenbeck approach * Full weight-bearing capacity prior to the trauma * Providing written informed consent Exclusion Criteria: * Age less than 18 years old * Fracture pattern not amenable to surgery through Kocher-Langenbeck approach * Lower extremity fracture ipsilateral to the acetabular fracture * Any traumatic injury that requires surgical management by other surgical specialty * Bilateral Acetabular Fractures * Limited weight bearing capacity prior to the trauma * Procedure performed under any anesthesia other than GETA * Chronic opioid use * History of Substance Abuse * Allergies or history of adverse reactions to any of the drugs used in the * Mental Disability * History of Psychiatric disorders
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Puerto Rico Medical Center
RECRUITINGSan Juan, 00935, Puerto Rico
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