Hip surgery pain relief: new nerve block shows promise
NCT ID NCT07023107
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a specific nerve block called PENG, using the numbing drug ropivacaine, could reduce surgical stress and pain after total hip replacement. Sixty older adults (ages 60-100) scheduled for hip surgery under spinal anesthesia received either the nerve block or a placebo (salt water). The main goal was to see if the block lowered inflammation markers in the blood and delayed the need for painkillers.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ropivacaine
- What this could lead to
- If it works, this could offer a better way to manage pain after hip replacement, reducing the need for strong opioids.
- What could go wrong
- This is a small, completed Phase 4 trial with only 60 participants, so results may not apply to everyone. The nerve block is a temporary procedure and does not change the underlying condition.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
60 people
The number who actually took part.
- Started
-
Jun 2025
- Finished
-
Dec 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
60 to 100 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with ASA classification I-III * Aged 60-100 years * Who will be scheduled for hip arthroplasty under spinal anesthesia Exclusion Criteria: * Patients who have a history of bleeding diathesis * Take anticoagulant therapy * History of chronic pain before surgery * Multiple trauma * patients unable to assess their pain (dementia) * patients operated under general anesthesia * patients having an infection in the region of the procedure * the patient who does not accept the procedure
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Poznan University of Medical Sciences
Poznan, Poland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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