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New hip pain block could cut opioid use in ER

NCT ID NCT05673486

Symptom relief Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a PENG nerve block—a targeted injection of anesthetic around the hip—can reduce pain and the need for morphine in adults with hip fractures in the emergency department. 36 patients were randomly assigned to receive either the block plus standard care or standard care alone. The goal was to see if the block provides better pain control and lowers opioid use.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
PENG nerve block (anesthetic injection around hip nerves)
What this could lead to
If it works, this could offer a better, faster way to manage hip fracture pain in the ER with less need for strong opioids.
What could go wrong
This is a small, early study with only 36 people, so results may not apply to everyone. The evidence for PENG blocks in the ER is still weak.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

36 people

The number who actually took part.

Started

Mar 2023

Finished

Dec 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult patients (≥18 years old) admitted to the emergency department for a hip fracture 2. Pain assessed by VAS/NRS ≥ 3 when the clinical suspicion of hip fracture is confirmed by the emergency physician 3. Patients capable of expressing his/her consent prior to participation in the study 4. Affiliated to or beneficiary of a social security regimen Exclusion Criteria: 1. Patients for who it is impossible to collect the pain assessment scale 2. Patients with known or suspected bleeding disorders : * Personal and family history of bleeding symptoms (spontaneous or induced) * Clinical signs suggesting a haemostasis disorder * Patient on anticoagulant at a curative dose with a very high risk of bleeding (labile International Normalized Ratio (INR), mechanical valve, acute kidney failure and treatment with direct oral anticoagulants) * Inherited bleeding disorder (Hemophilia A, Hemophilia B, Von Willebrand disease, Fibrinogen deficiency, Factor XII deficiency) * Pathologies that may interfere with hemostasis: advanced liver disease, decompensated hematological disease, collagen diseases such as Ehlers-Danlos disease 3. Patients in whom it is impossible to perform the PENG-Block: Body Mass Index (BMI) \> 40, adenopathy or infection at the puncture site, allergy to the anesthetics used 4. Pregnant, parturient or breastfeeding women 5. Patients under judicial protection or judicial safeguard 6. Any other reason which, in the opinion of the investigator, could interfere with the evaluation of the study objectives

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Conditions

The condition(s) this trial relates to.

Emergencies femoral neck fracture hip fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hip fractures

Contacts and locations

Locations

  • Hyères Hospital

    Hyères, Var, 83400, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.