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New combo shows promise for rare eye cancer, but not a cure

NCT ID NCT05282901

First seen Dec 12, 2025 · Last updated Jun 13, 2026 · Updated 20 times

Summary

This study tests two drugs, pembrolizumab and lenvatinib, in people with metastatic uveal melanoma, a rare eye cancer that has spread. The goal is to see if the combination can slow tumor growth. The trial includes two groups: those who have not had a prior treatment called Tebentafusp, and those who have. Participants will receive the drugs and be monitored with scans every 9 weeks. This is not a cure; treatment is ongoing to control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Institut Curie

    Paris, 75005, France

Conditions

The condition(s) this trial relates to.

melanoma Neoplasm Metastasis uveal melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.