New drug combo could shrink head and neck tumors before surgery
NCT ID NCT05977907
First seen Mar 14, 2026 · Last updated May 24, 2026 · Updated 9 times
Summary
This study tests whether giving two drugs (pembrolizumab and IO102-103) before surgery is safe and effective for people with head and neck cancer. About 30 adults with removable tumors will receive the drug combination, then have surgery. Researchers will monitor side effects and tumor shrinkage to see if the approach improves outcomes.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Northwestern Memorial Hospital
NOT_YET_RECRUITINGChicago, Illinois, 60611, United States
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Providence Cancer Institute
NOT_YET_RECRUITINGPortland, Oregon, 97213, United States
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Sibley Memorial Hospital
NOT_YET_RECRUITINGWashington D.C., District of Columbia, 20016, United States
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Thomas Jefferson University Hospital
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact
Conditions
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