New drug duo before surgery shows promise against head and neck cancer

NCT ID NCT05977907

First seen Mar 14, 2026 · Last updated May 17, 2026 · Updated 8 times

Summary

This study tests whether giving two drugs (pembrolizumab and IO102-103) before surgery is safe and effective for people with head and neck cancer that can be removed. About 30 adults with newly diagnosed or returning cancer will receive the drugs and then have surgery. Researchers will watch for side effects and check how much the tumor shrinks after treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwestern Memorial Hospital

    NOT_YET_RECRUITING

    Chicago, Illinois, 60611, United States

    Contact

  • Providence Cancer Institute

    NOT_YET_RECRUITING

    Portland, Oregon, 97213, United States

    Contact

  • Sibley Memorial Hospital

    NOT_YET_RECRUITING

    Washington D.C., District of Columbia, 20016, United States

    Contact

  • Thomas Jefferson University Hospital

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

    Contact

Conditions

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