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Promising new combo offers hope for rare, aggressive ovarian cancer

NCT ID NCT04602377

First seen Jan 06, 2026 · Last updated Jun 17, 2026 · Updated 27 times

Summary

This study tests whether adding an immunotherapy drug (pembrolizumab) to standard chemotherapy can improve outcomes for people with a rare and aggressive ovarian cancer called small cell ovarian carcinoma of hypercalcemic type. The trial aims to increase the chance of complete remission and allow more patients to receive intensive chemotherapy. About 27 participants aged 12 and older with untreated disease will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Limoges - Hôpital Dupuytren

    RECRUITING

    Limoges, 87042, France

    Contact

  • Centre Georges François Leclerc

    ACTIVE_NOT_RECRUITING

    Dijon, 21079, France

  • Centre Hospitalier Régional Universitaire de Besançon

    ACTIVE_NOT_RECRUITING

    Besançon, 25030, France

  • Centre Hospitalier Universitaire d'Angers

    ACTIVE_NOT_RECRUITING

    Angers, 49933, France

  • Centre Léon Bérard

    RECRUITING

    Lyon, 69373, France

    Contact

  • Centre Oscar Lambret

    ACTIVE_NOT_RECRUITING

    Lille, 59020, France

  • Gustave Roussy

    RECRUITING

    Villejuif, 94805, France

    Contact

  • Hôpital de Hautepierre

    NOT_YET_RECRUITING

    Strasbourg, France

    Contact

  • ICANS - Institut de cancérologie Strasbourg Europe

    RECRUITING

    Strasbourg, 67033, France

    Contact

  • ICM Val d'Aurelle

    WITHDRAWN

    Montpellier, 34298, France

  • ICO - Paul Papin

    RECRUITING

    Angers, 49055, France

    Contact

  • Institut Bergonié

    ACTIVE_NOT_RECRUITING

    Bordeaux, 33076, France

  • Oncopole Claudius Regaud - IUCT Oncopole

    RECRUITING

    Toulouse, 31059, France

    Contact

Conditions

The condition(s) this trial relates to.

ovarian small cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.