Promising new combo offers hope for rare, aggressive ovarian cancer

NCT ID NCT04602377

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding an immunotherapy drug (pembrolizumab) to standard chemotherapy can improve outcomes for people with a rare and aggressive ovarian cancer called small cell ovarian carcinoma of hypercalcemic type. The trial aims to increase the chance of complete remission and allow more patients to receive intensive chemotherapy. About 27 participants aged 12 and older with untreated disease will be enrolled.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Limoges - Hôpital Dupuytren

    RECRUITING

    Limoges, 87042, France

  • Centre Georges François Leclerc

    ACTIVE_NOT_RECRUITING

    Dijon, 21079, France

  • Centre Hospitalier Régional Universitaire de Besançon

    ACTIVE_NOT_RECRUITING

    Besançon, 25030, France

  • Centre Hospitalier Universitaire d'Angers

    ACTIVE_NOT_RECRUITING

    Angers, 49933, France

  • Centre Léon Bérard

    RECRUITING

    Lyon, 69373, France

  • Centre Oscar Lambret

    ACTIVE_NOT_RECRUITING

    Lille, 59020, France

  • Gustave Roussy

    RECRUITING

    Villejuif, 94805, France

  • Hôpital de Hautepierre

    NOT_YET_RECRUITING

    Strasbourg, France

  • ICANS - Institut de cancérologie Strasbourg Europe

    RECRUITING

    Strasbourg, 67033, France

  • ICM Val d'Aurelle

    WITHDRAWN

    Montpellier, 34298, France

  • ICO - Paul Papin

    RECRUITING

    Angers, 49055, France

  • Institut Bergonié

    ACTIVE_NOT_RECRUITING

    Bordeaux, 33076, France

  • Oncopole Claudius Regaud - IUCT Oncopole

    RECRUITING

    Toulouse, 31059, France