Friends helping friends: new study shows peer power in HIV prevention
NCT ID NCT04982250
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new way to help young women in Kenya start PrEP, a daily pill that prevents HIV. Young women already taking PrEP were trained to refer their friends and give them HIV self-test kits. The goal was to see if this peer-led approach could increase PrEP use among those at high risk. The study involved 211 participants and compared this enhanced method to the usual word-of-mouth referrals.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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211 people
The number who actually took part.
- Started
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Feb 2022
- Finished
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Aug 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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16 to 24 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: For peer providers (qualitative data, pilot): * Age ≥16 to 24 years\* * Female * Have been on PrEP for a minimum of three months * Good adherence to PrEP (i.e., self-report take PrEP all the time) * Willing to disclose PrEP use to their peers * Able to identify up to 4 peers at risk of HIV infection * Willing to participate in training with study counselors on PrEP referral and HIVST use * Willing to refer peers to PrEP and deliver HIVSTs * Able and willing to provide written informed consent * Per the discretion of the site investigator, no clear risks of social harm or inability otherwise to reasonably conduct HIVST at home in the context of PrEP delivery For peer providers (cRCT): * Age ≥16 to 24 years\* * Female * Must have refilled or initiated PrEP (i.e., been dispensed PrEP) * Not currently enrolled in an HIV study * Able to identify up to 4 peers with recent self-reported behaviors associated with risk of HIV acquisition * Willing to participate in training with study counselors on PrEP referral and HIVST use * Willing to refer peers to PrEP and deliver HIVSTs * Able and willing to provide written informed consent * Willing to provide contact information for follow-up * Willing to engage in all research activities including completion of questionnaires * Per the discretion of the site investigator, no clear risks of social harm or inability otherwise to reasonably conduct HIVST at home in the context of PrEP delivery For peer clients (pilot, RCT): * Age ≥16 to 24 years\* * Female * Referred by peer (i.e., a PrEP users) to initiate PrEP * Able and willing to provide informed consent * NOTE: We will only enroll young women ≥16 to 17 years into the study if they are emancipated minors and thus able to legally provide consent for participation in research. Kenyan law acknowledges women ages 14 to 17 who have become pregnant as emancipated minors. The PHRD site/UW collaboration has successfully enrolled emancipated minors into a number of prior studies, including PrEP clinical trials. In addition, Kenya's national policy guidelines explicitly permit PrEP use in this age group. Exclusion Criteria: For peer providers (qualitative data, pilot): * Age ≥16 or \>24 years * Male * Have not used PrEP for a minimum of three months * Not willing to disclose PrEP use to their peers * Not able to identify up to 4 peers at risk of HIV infection * Not willing to participate in training with study counselors on PrEP referral and HIVST use * Not willing to refer peers to PrEP and deliver HIVSTs * Not able and willing to provide written informed consent For peer providers (cRCT): * Age ≥16 or \>24 years * Male * Have not used PrEP * Currently enrolled in an HIV study * Not able to identify up to 4 peers at risk of HIV infection * Illiterate * Not willing to participate in training with study counselors on PrEP referral and HIVST use * Not willing to refer peers to PrEP and deliver HIVSTs * Not able and willing to provide written informed consent For peer clients (pilot, cRCT): * Age ≥16 or \>24 years * Male * Not referred by peer (i.e., a PrEP users) to initiate PrEP * Not able and willing to provide written informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Partners in Health and Research Development
Thika, Kenya
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Other studies related to the condition(s) this trial covers.
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