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Friends helping friends: new study shows peer power in HIV prevention

NCT ID NCT04982250

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new way to help young women in Kenya start PrEP, a daily pill that prevents HIV. Young women already taking PrEP were trained to refer their friends and give them HIV self-test kits. The goal was to see if this peer-led approach could increase PrEP use among those at high risk. The study involved 211 participants and compared this enhanced method to the usual word-of-mouth referrals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

211 people

The number who actually took part.

Started

Feb 2022

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 24 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: For peer providers (qualitative data, pilot): * Age ≥16 to 24 years\* * Female * Have been on PrEP for a minimum of three months * Good adherence to PrEP (i.e., self-report take PrEP all the time) * Willing to disclose PrEP use to their peers * Able to identify up to 4 peers at risk of HIV infection * Willing to participate in training with study counselors on PrEP referral and HIVST use * Willing to refer peers to PrEP and deliver HIVSTs * Able and willing to provide written informed consent * Per the discretion of the site investigator, no clear risks of social harm or inability otherwise to reasonably conduct HIVST at home in the context of PrEP delivery For peer providers (cRCT): * Age ≥16 to 24 years\* * Female * Must have refilled or initiated PrEP (i.e., been dispensed PrEP) * Not currently enrolled in an HIV study * Able to identify up to 4 peers with recent self-reported behaviors associated with risk of HIV acquisition * Willing to participate in training with study counselors on PrEP referral and HIVST use * Willing to refer peers to PrEP and deliver HIVSTs * Able and willing to provide written informed consent * Willing to provide contact information for follow-up * Willing to engage in all research activities including completion of questionnaires * Per the discretion of the site investigator, no clear risks of social harm or inability otherwise to reasonably conduct HIVST at home in the context of PrEP delivery For peer clients (pilot, RCT): * Age ≥16 to 24 years\* * Female * Referred by peer (i.e., a PrEP users) to initiate PrEP * Able and willing to provide informed consent * NOTE: We will only enroll young women ≥16 to 17 years into the study if they are emancipated minors and thus able to legally provide consent for participation in research. Kenyan law acknowledges women ages 14 to 17 who have become pregnant as emancipated minors. The PHRD site/UW collaboration has successfully enrolled emancipated minors into a number of prior studies, including PrEP clinical trials. In addition, Kenya's national policy guidelines explicitly permit PrEP use in this age group. Exclusion Criteria: For peer providers (qualitative data, pilot): * Age ≥16 or \>24 years * Male * Have not used PrEP for a minimum of three months * Not willing to disclose PrEP use to their peers * Not able to identify up to 4 peers at risk of HIV infection * Not willing to participate in training with study counselors on PrEP referral and HIVST use * Not willing to refer peers to PrEP and deliver HIVSTs * Not able and willing to provide written informed consent For peer providers (cRCT): * Age ≥16 or \>24 years * Male * Have not used PrEP * Currently enrolled in an HIV study * Not able to identify up to 4 peers at risk of HIV infection * Illiterate * Not willing to participate in training with study counselors on PrEP referral and HIVST use * Not willing to refer peers to PrEP and deliver HIVSTs * Not able and willing to provide written informed consent For peer clients (pilot, cRCT): * Age ≥16 or \>24 years * Male * Not referred by peer (i.e., a PrEP users) to initiate PrEP * Not able and willing to provide written informed consent

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Partners in Health and Research Development

    Thika, Kenya

More trials for these conditions

Other studies related to the condition(s) this trial covers.