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Stem cells and immunotherapy join forces against childhood brain tumors

NCT ID NCT07031765

First seen Sep 30, 2025 · Last updated Jun 16, 2026 · Updated 41 times

Summary

This early-stage trial tests a new approach for children whose high-grade glioma has come back after standard treatments. It combines specially grown stem cells with an immunotherapy drug called nivolumab. The main goals are to see if the treatment is safe and possible to deliver, not yet to prove it works. Only 12 children will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UF Health Shands Children's Hospital/Shands Hospital

    Gainesville, Florida, 32608, United States

Conditions

The condition(s) this trial relates to.

anaplastic astrocytoma astrocytoma (excluding glioblastoma) ependymoma glioblastoma glioma malignant glioma oligoastrocytoma oligodendroglioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.