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Which pain block works best for kids after appendix removal?

NCT ID NCT07301528

Symptom relief Sponsor: Zeycan Kahya Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two types of nerve blocks—erector spinae plane (ESP) and quadratus lumborum (QL)—to see which provides better pain relief after appendix surgery in children aged 3-13. Sixty children received one of the blocks along with general anesthesia. Researchers measured pain scores, opioid use, and recovery times. The goal is to help doctors choose the best option for reducing pain and opioid needs in kids.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If one block proves better, it could lead to less pain and fewer opioids for children after appendix surgery.
What could go wrong
This is a small, completed trial with only 60 children. Results may not apply to all hospitals or age groups. Both blocks are already used, so no major breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Dec 2025

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

3 to 13 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 3-13 years * Diagnosis of acute appendicitis requiring appendectomy * ASA physical status I-II * Planned general anesthesia with intraoperative regional block (ESP or QL block) * Written informed consent obtained from parents or legal guardians Exclusion Criteria: * Refusal of regional block by family or anesthesia team * Coagulopathy or anticoagulant medication use * Local infection at the block injection site * Known allergy or contraindication to local anesthetics * Neurological or neuromuscular disorders * Cognitive impairment preventing postoperative pain assessment * Conversion to open surgery * Intraoperative complications requiring deviation from study protocol

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Conditions

The condition(s) this trial relates to.

appendicitis Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Erector spinae block Quadratus lumborum nerve block

Contacts and locations

Locations

  • Kutahya City Hospital

    Kütahya, 43100, Turkey (Türkiye)

  • Kutahya City Hospital Anesthesia and Reanimation Department

    Kütahya, Kütahya, 43100, Turkey (Türkiye)

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