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New study tests safer, faster fertility option for PCOS patients

NCT ID NCT07171970

Disease control Sponsor: Mỹ Đức Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two fertility treatments for women with polycystic ovary syndrome (PCOS): a simpler in vitro maturation (IVM) method with fresh embryo transfer versus standard in vitro fertilization (IVF) with frozen embryo transfer. The goal is to see which approach leads to more live births while reducing risks like ovarian hyperstimulation syndrome. About 600 women will take part, and the results could help doctors choose the best, safest option for PCOS patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
estradiol valerate, progesterone, dydrogesterone, follicle-stimulating hormone (FSH)
What this could lead to
If successful, this could offer women with PCOS a simpler, safer fertility treatment that avoids the risk of ovarian hyperstimulation syndrome and reduces time to pregnancy.
What could go wrong
This is a single-center trial, and results may not apply to all clinics. The IVM approach may have lower success rates than IVF, and fresh transfer could increase cycle cancellation risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 600 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Jan 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 42 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged 18 - 42 years old. * Diagnosed with PCOS, followed Rotterdam 2003 criteria (Group TREP consensus workshop, 2004) * Had fewer than three previous failed frozen embryo transfer (FET) cycles * Transferred no more than two cleavage embryos or one good-quality blastocyst or no more than two poor-quality blastocysts. * Agreeing to participate in the study Exclusion Criteria: * Having allergy and contraindications for exogenous hormone administration (e.g., breast cancer, thromboembolic disease) * Cycles with preimplantation genetic testing indication * Oocyte donation cycles * Having untreated uterine or adnexal abnormalities (e.g., intrauterine adhesions, unicornuate/ bicornuate/ arcuate uterus, large leiomyoma ≥5 cm in diameter; adenomyosis, endometrial polyp, hydrosalpinx).

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Conditions

The condition(s) this trial relates to.

polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Fresh embryo transfer In vitro maturation of oocytes Polycystic ovary syndrome (PCOS)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • IVFMD - My Duc Hospital

    RECRUITING

    Ho Chi Minh City, Vietnam

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