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New hope for Hard-to-Treat breast cancer: targeted drug shows promise in early trial

NCT ID NCT04965766

First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 19 times

Summary

This study tests an experimental drug called patritumab deruxtecan in people with advanced breast cancer that is hormone-receptor positive but no longer responds to hormone therapy or CDK4/6 inhibitors. About 139 participants will receive the drug every three weeks to see if it shrinks tumors and how safe it is. Researchers will also study biomarkers to understand who benefits most.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Limoges

    RECRUITING

    Limoges, 87042, France

    Contact

  • Centre Antoine Lacassagne

    RECRUITING

    Nice, 06189, France

    Contact

  • Centre Georges François Leclerc

    ACTIVE_NOT_RECRUITING

    Dijon, 21079, France

  • Centre Léon Bérard

    RECRUITING

    Lyon, 69373, France

    Contact

  • Gustave Roussy

    RECRUITING

    Villejuif, 94805, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Tenon

    RECRUITING

    Paris, 75020, France

    Contact

  • Institut Claudius Regaud

    RECRUITING

    Toulouse, 31059, France

    Contact

  • Institut Curie

    RECRUITING

    Paris, 75005, France

    Contact

  • Institut Paoli Calmettes

    RECRUITING

    Marseille, 13273, France

    Contact

  • Institut Régional du Cancer de Montpellier

    RECRUITING

    Montpellier, 34298, France

    Contact

  • Institut de Cancérologie de l'Ouest

    RECRUITING

    Saint-Herblain, 44805, France

    Contact

Conditions

Explore the condition pages connected to this study.