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New study aims to decode hidden breathing conflicts in ICU patients

NCT ID NCT07624786

Knowledge-focused Sponsor: Erasmus Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This observational study will analyze data from 110 mechanically ventilated patients to understand how often their breathing is out of sync with the ventilator. Researchers will use special software to detect these mismatches and see if they relate to patient outcomes. The goal is to gather knowledge, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 110 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients admitted to the ICU that receive invasive mechanical ventilation.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \> 18 years old. * Recordings available of ventilator waveforms synchronized with the patient's electronic health record during invasive mechanical ventilation. * Duration of mechanical ventilation of at least 24 hours. Exclusion Criteria: * (Previous) registered objection of patient and/or relatives to re-use clinical data for research purposes * No consent for re-use of data for research

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Conditions

The condition(s) this trial relates to.

Patient-Ventilator Asynchrony

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mechanical ventilation Patient-ventilator asynchrony

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Catharina Ziekenhuis Eindhoven (CZE)

    RECRUITING

    Eindhoven, North Brabant, 5623EJ, Netherlands

  • Erasmus Medical Center (EMC)

    RECRUITING

    Rotterdam, South Holland, 3015GD, Netherlands

  • Leiden University Medical Center (LUMC)

    NOT_YET_RECRUITING

    Leiden, South Holland, 2333ZA, Netherlands

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