New brain scan could end misdiagnosis of Parkinson's and tremor
NCT ID NCT04265209
First seen Nov 17, 2025 · Last updated Jun 23, 2026 · Updated 31 times
Summary
This study tested a new PET scan tracer, [18F] LBT-999, to see if it can distinguish Parkinson's disease from essential tremor as well as the current standard SPECT scan. Researchers compared the two imaging methods in 152 patients. If the PET scan works equally well, it could offer a more precise and potentially faster diagnosis.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHRU Hôpital Bretonneau
Tours, 37044, France
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CHU Bordeaux
Bordeaux, 33076, France
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CHU La Pitié Salpêtrière
Paris, 75013, France
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CHU La Timone
Marseille, 13005, France
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CLCC Georges-François Leclerc C.G.F.L
Dijon, 21000, France
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Centre Eugène Marquis / CHU Pontchaillou
Rennes, 35000, France
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Centre Hospitalier Universitaire de Nîmes
Nîmes, 30029, France
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Centre Jean PERRIN / Hôpital Gabriel Montpied (CHU)
Clermont-Ferrand, 63000, France
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Hospices Civils de Lyon
Lyon, 69500, France
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Hôpital Avicenne
Bobigny, 93000, France
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Hôpital Brabois / Hôpital Central (CHRU Nancy)
Nancy, France
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Hôpital Henri Mondor
Créteil, 94010, France
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Hôpital Laennec (CHU Nantes)
Nantes, 44093, France
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Hôpital Pierre Paul Riquet - Purpan (CHU)
Toulouse, 3100, France
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Hôpital Roger Salengro (CHRU de Lille)
Lille, 59037, France
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Institut de cancérologie Strasbourg Europe
Strasbourg, 67033, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
[18F] LBT-999 (a radioactive tracer for PET imaging)
What this could lead to
If successful, this could provide a more accurate and accessible way to diagnose Parkinson's disease versus essential tremor, helping patients get the right treatment sooner.
What could go wrong
This is a completed Phase 3 study, but the new PET tracer may not prove as effective as the standard SPECT method. Also, PET scanners are less widely available than SPECT, limiting real-world use.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.