Brain mapping study could make Parkinson's treatment smarter
NCT ID NCT05568199
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to understand how different brain circuits affect movement and thinking in people with Parkinson's disease who already have a deep brain stimulation (DBS) device. Researchers will measure brain activity patterns during rest and movement, and link them to motor and cognitive test results. The goal is to gather knowledge that could one day help doctors fine-tune DBS settings for each patient. About 100 adults with Parkinson's and a DBS implant will take part.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2024
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Potential participants are identified by clinicians and trained research personnel through the movement disorder clinic. Patients are identified during the University of Minnesota DBS surgery candidacy evaluation process.
- Ages
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21 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Implanted with a DBS system * Existing 7T imagery (either done as standard-of-care or done as part of Noam Harel's study, IRB #1210M22183) * Diagnosed with idiopathic Parkinson's Disease * Minimum age 21 years Exclusion Criteria: * Other significant neurological disorder, as determined by PI * Diagnosis of dementia * Pregnant
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Brain imaging may reveal who benefits from deep brain stimulation for Parkinson's freezing
- Brain implant for Parkinson's may raise fall risk — a study investigates
- Gentle touch may ease sleepless nights for Parkinson's patients
- Brain zap study reveals hidden motivation switches in Parkinson's