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Can teaching parents to talk about sex protect LGBTQ teens?

NCT ID NCT07825571

Prevention Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

Researchers at the University of Pennsylvania are testing a five-session group program called GIST that trains parents of transgender, gender diverse, lesbian, and bisexual female youth to discuss sexuality and health. The trial enrolls 300 parents and their 12- to 18-year-old children in the United States. The study measures how much and how well families communicate about topics like coming out, condom use, and peer pressure, and tracks depression symptoms in both parents and teens.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a five-session group program that trains parents to talk with their LGBTQ teens about sexuality and health
What this could lead to
If it works, this could give families a practical way to talk about sexuality and health, which may help lower HIV and STI risk for LGBTQ youth.
What could go wrong
Better parent-teen communication may not translate into lower infection rates, and the trial measures communication and mental health rather than HIV or STI diagnoses. Results may not apply to families outside the United States.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

12 to 100 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Youth participants are: identify as transgender or gender diverse, or lebian or bisexual female be between ages 12-18 years able to comprehend spoken English resides in the United States consents or assents to study participation Parent participants are: the parent, legal guardians, legal custodians (hereinafter "parent") of index youth age 18 or older able to comprehend spoken English resides in the United States consents to study participation consents to their child's study participation Exclusion Criteria: Excluded youth participants are: non-transgender or gender diverse or lesbian or bisexual female youth Excluded participants are: parents whose child does not meet eligibility criteria

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Communication about health information HIV/sti incidence

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Penn Nursing

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

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