New study tests if a simpler pain block beats epidural for esophageal cancer recovery
NCT ID NCT07434739
First seen Jun 27, 2026 · Last updated Sep 15, 2026 · Updated 2 times
Summary
This study compares two ways to manage pain after minimally invasive surgery for esophageal cancer: a paravertebral catheter versus the standard epidural. The goal is to see if the paravertebral approach provides similar or better recovery quality by day three. About 506 adults having this surgery will take part, and researchers will measure pain control, mobility, and side effects like low blood pressure.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 506 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Nov 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient requiring totally minimally invasive surgical esophagectomy (robot-assisted or not) with 2 Ivor-Lewis type approaches: laparoscopy for the abdominal approach and thoracoscopy for the thoracic approach. * Age ≥ 18 years old * Patient who has given written consent to participate in the trial * Socially insured patient * Patient willing to comply with all study procedures and duration Exclusion Criteria: * \- Intervention planned by open esophagectomy (laparotomy and/or thoracotomy) * 3-stage esophagectomy, McKeown type * Obesity with body mass index ≥ 35 kg.m-2 (due to the foreseeable difficulties arising from this BMI). * Pregnancy * Haemostasis trouble * ASA score \> 3 * Renal failure (eGFR \< 50 mL/min) * Ongoing opioid use (\>3 months prior to the day of surgery) * Contraindication to local anesthesia * Local infection * Inability to receive informed information * Person deprived of the liberty * Person benefiting from a system of legal protection (guardianship…)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU de Lille
RECRUITINGLille, France
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