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New nerve block may ease knee surgery pain without slowing you down

NCT ID NCT05566561

Symptom relief Sponsor: Medipol University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a special nerve block called the parasartorial compartment block to see if it reduces pain after knee surgery. Sixty adults having knee surgery under spinal anesthesia received the block plus standard painkillers. Researchers measured pain scores and how much extra pain medicine was needed. The goal is to find a way to control pain without affecting leg movement, which could help people get moving sooner after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
parasartorial compartment block (nerve block)
What this could lead to
If effective, this nerve block could provide better pain relief after knee surgery without affecting leg movement, helping patients recover faster.
What could go wrong
This is a small, completed study with only 60 participants. The results may not apply to everyone, and nerve blocks carry risks like infection or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Oct 2022

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with ASA classification I-III, * Aged 18-75 years * Who will be scheduled for knee surgery under spinal anesthesia. Exclusion Criteria: * Patients who have a history of bleeding diathesis, * Take anticoagulant therapy, * History of chronic pain before surgery, * Multiple trauma, * Who cannot assess their pain, * Who have been operated under spinal anesthesia, * Who have an infection in the area and do not accept the procedure

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Conditions

The condition(s) this trial relates to.

Knee Injuries osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee arthritis Knee disease Knee injuries Knee osteoarthritis

Contacts and locations

Locations

  • Istanbul Medipol University Hospital

    Istanbul, Bagcilar, 34070, Turkey (Türkiye)

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