Papaya leaf extract tested as dengue treatment for kids
NCT ID NCT07172100
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether papaya leaf extract syrup can raise low platelet counts in children aged 2–12 with dengue fever. One hundred children will receive either standard care alone or standard care plus the extract for three days. Researchers will compare platelet changes and whether fewer children need transfusions or intensive care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- papaya leaf extract
- What this could lead to
- If it works, this could offer a simple, natural way to help children with dengue recover faster and avoid platelet transfusions.
- What could go wrong
- This is a small, early-stage trial (100 children). The extract may not work better than standard care, and some children may have allergic reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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2 to 12 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with dengue fever * Patients from age 2 till 2 years of age Exclusion Criteria: * Patients hypersensitive to papaya leaf extract * Patients with bleeding disorder
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Guzel Maxood
Karachi, Pakistan
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