New drain test may spot pancreatic leaks faster
NCT ID NCT02784990
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether measuring a pancreatic enzyme called lipase in surgical drains can help doctors detect pancreatic fistula earlier and more accurately than the current standard test (amylase). Researchers collected drain fluid and blood samples from 770 adults who had pancreatic surgery. The goal was to see if lipase levels could better predict which patients would develop a fistula with serious symptoms within 30 days after surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
770 people
The number who actually took part.
- Started
-
Jun 2016
- Finished
-
Nov 2020
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients undergoing scheduled pancreatic resection
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients over 18 * Patients undergoing scheduled pancreatic resection with or without anastomosis (cephalic duodenopancreatectomy, median pancreatectomy, left pancreatectomy, enucleation) * Patients able to understand instructions/information * Patients who have provided written informed consent * Patients with Health Insurance cover Exclusion Criteria: * Patients with scheduled total pancreatectomy * Adults under wardship * Pregnant or breast-feeding women * Total pancreatectomy * Pancreatectomy not feasible
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Pancreatic fistula are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
APHM - Institut Paoli-Calmettes
Marseille, 13009, France
-
CHU Dijon Bourgogne
Dijon, 21079, France
-
CHU Grenoble Alpes
La Tronche, 38700, France
-
CHU Jean Minjoz
Besançon, 25030, France
-
CHU William MOREY
Chalon-sur-Saône, 71321, France
-
CHU de NANCY
Vandœuvre-lès-Nancy, 54511, France
-
CHU de REIMS - Hôpital Robert Debré
Reims, 51100, France
-
HCL - Hôpital universitaire de la Croix Rousse
Lyon, 69317, France
-
Hopital Claude Huriez
Lille, 59037, France
-
Hôpital Hautepierre
Strasbourg, 67098, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Scientists hunt for clues to prevent a common complication after pancreatic cancer surgery
- Early warning probe could save lives after pancreatic surgery
- Blood marker may forecast deadly pancreatic surgery complications
- Could a simple injection stop pancreatic leaks after surgery?
- Radiation before pancreatic surgery may prevent dangerous leaks
- Simple stent may cut pancreatic leak risk after major surgery