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New study aims to spot which pancreatic cysts turn cancerous

NCT ID NCT01202136

Diagnosis Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 477 adults with pancreatic cysts to find better ways to tell which cysts are harmless and which might become cancer. Researchers combined medical images, patient history, and fluid from the cysts to create a more accurate prediction model. The goal is to help doctors decide when surgery or monitoring is needed, avoiding unnecessary procedures while catching cancer early.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

477 people

The number who actually took part.

Start date

Oct 2012

Finished

Sep 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients referred to Johns Hopkins for evaluation of pancreatic cysts

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult patients age 18 years and older 2. Referred for assessment of one or more pancreatic cyst. Exclusion Criteria: 1. Medically ill patients with ASA class 4 or greater. 2. History of chronic kidney disease with a serum creatinine \> 2.0 mg/dl or estimated glomerulofiltration rate (eGFR) \< 30 ml/min, dialysis patients, acute renal failure, cirrhosis of the liver, chronic hepatitis, prior nephrectomy or kidney or liver transplantation. 3. History of moderate (generalized hives) or severe (facial swelling, airway reaction) reaction to intravenous radiographic contrast material. 4. History of obstruction in the upper GI tract such as esophageal or pyloric stricture, which would not allow passage of an endoscope. 5. Bleeding diathesis (clotting problems) or a history of thrombocytopenia (low platelet count \<50,000). 6. Inability to provide informed consent. 7. Pregnancy or lactation.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm Pancreatic Cyst pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pancreatic cancer Pancreatic cysts

Contacts and locations

Locations

  • Johns Hopkins Hospital

    Baltimore, Maryland, 21231, United States

  • Johns Hopkins Medicine

    Baltimore, Maryland, 21287, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.