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New MRI dye could help detect pancreatic cancer early

NCT ID NCT05873699

Diagnosis Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused This study
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 5 times

Summary

This pilot study tests whether a special MRI dye called hyperpolarized 13-C-pyruvate can help doctors tell the difference between harmless and dangerous pancreatic cysts. About 20 adults with pancreatic cysts who are scheduled for surgery will receive the dye and have an MRI scan. The goal is to see if the dye is safe and if it can improve detection of high-risk cysts before surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Hyperpolarized 13-C-pyruvate (a special MRI dye given by injection)
What this could lead to
If it works, this could help doctors better identify which pancreatic cysts are dangerous and need surgery, avoiding unnecessary operations.
What could go wrong
This is a very early, small pilot study (20 people) focused on safety and imaging feasibility. The dye may not clearly distinguish cyst types, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2023

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients ≥ 18 years old. Patients under 18 are excluded due to their potential inability to understand and consent independently to the methods required for the study drug use and its potential risks and benefits. * Patients with pancreatic cyst/s * Patients who will undergo surgical resection (or cyst wall biopsy) of pancreatic cysts * Patients able to understand and willing to sign a written informed consent document * Both English-speaking and non-English-speaking patients are eligible for participation Exclusion Criteria: * Contraindication to MRI * Electrically, magnetically, or mechanically activated implants that would preclude MRI * Allergy to Gadavist IV contrast * History of cardiac arrhythmias * Pregnancy or breastfeeding women * Women of child-bearing age that are sexually active and not using birth control * Cognitively impaired individuals * Weight above 260 pounds (lbs)

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Conditions

The condition(s) this trial relates to.

cystic tumor of the pancreas Pancreatic Cyst

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pancreatic cyst

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

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