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Age alone Shouldn't decide: study suggests surgery may help fit octogenarians with pancreatic cancer

NCT ID NCT07542782

Knowledge-focused Sponsor: Medizinische Hochschule Brandenburg Theodor Fontane Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at over 2,000 older adults (80+) with pancreatic cancer that hadn't spread, all in good general health. Researchers compared those who had surgery to remove the tumor with those who didn't, using data from a German cancer registry. The goal was to see if surgery could improve survival and help doctors focus on a patient's fitness rather than just their age when making treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the findings are confirmed, doctors may become more willing to offer surgery to otherwise healthy older patients with pancreatic cancer, potentially improving their survival chances.
What could go wrong
This is a retrospective registry analysis, not a controlled trial. The results show associations, not proof that surgery causes better survival. Unmeasured factors could influence the outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

2,048 people

The number who actually took part.

Started

Jan 2017

Finished

Oct 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All residents of the Federal States Brandenburg and Berlin

Ages

18 to 89 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of invasive pancreatic carcinoma * UICC stage I-III * No distant metastases (M0) * ECOG performance status 0-1 * Diagnosis between Jan 1, 2017 and Dec 31, 2023 * Residence in Berlin or Brandenburg Exclusion Criteria: * Neuroendocrine tumors * Sarcomas

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pancreatic cancer

Contacts and locations

Locations

  • Medical School Brandenburg

    Brandenburg an der Havel, Brandenburg, 14770, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.