New cocktail therapy aims to improve pancreatic cancer surgery success
NCT ID NCT03563248
First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 29 times
Summary
This study tests whether adding losartan (a blood pressure drug) and nivolumab (an immunotherapy) to standard chemotherapy and radiation can improve surgical outcomes for people with localized pancreatic cancer. About 168 participants with borderline resectable or locally advanced tumors will receive the combination before surgery. The main goal is to see if more tumors can be removed with clear margins (R0 resection).
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Brigham and Women's Hospital
Boston, Massachusetts, 02215, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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New York University Langone Medical Center
New York, New York, 10016, United States
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Newton Wellesley Hospital
Newton, Massachusetts, 02462, United States
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Sibley Memorial Hospital
Washington D.C., District of Columbia, 20016, United States
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The Johns Hopkins Hospital
Baltimore, Maryland, 21287, United States
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University of Colorado Cancer Center
Aurora, Colorado, 80045, United States
Conditions
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