Precision radiation may offer better pain relief for spine metastases
NCT ID NCT02800551
First seen Feb 01, 2026 · Last updated Jun 23, 2026 · Updated 24 times
Summary
This study tested whether a more intense, precisely targeted type of radiation (SBRT) works better than standard radiation for reducing pain from cancer that has spread to the spine. About 219 adults with painful spinal metastases took part. The main goal was to see if SBRT leads to greater pain improvement at 6 months.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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UniversitätsSpital Zürich, Klinik für Radio-Onkologie
Zurich, 8091, Switzerland
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy (stereotactic body radiation therapy vs. conventional 3D conformal radiotherapy)
What this could lead to
If it works, this could provide better and longer-lasting pain relief for people with cancer that has spread to the spine, potentially improving quality of life.
What could go wrong
This is a phase 2 trial, so results are still preliminary. The higher radiation dose might also cause more side effects, and the benefit may not be large enough to change standard practice.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.