Pill combo boosts dental numbing for excruciating toothache
NCT ID NCT07146997
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 30 times
Summary
This study tested if taking ibuprofen and serratiopeptidase before a dental numbing shot helps it work better for people with severe tooth pain (irreversible pulpitis). 96 adults were split into four groups: placebo, ibuprofen alone, serratiopeptidase alone, or both. Pain was measured during drilling and root canal treatment. The goal was to see if the combination reduces pain and improves numbing success.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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HITEC-IMS Taxila
Rawalpindi, Punjab Province, 47080, Pakistan
Conditions
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