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New pain combo cuts opioid need after bariatric surgery

NCT ID NCT07380503

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding a drug called dexmedetomidine to a standard numbing medicine (bupivacaine) could improve pain control after weight loss surgery in severely obese patients. 78 adults having laparoscopic bariatric surgery received an ultrasound-guided nerve block with either bupivacaine alone or bupivacaine plus different doses of dexmedetomidine. The main goal was to see if the combination reduced the need for opioid painkillers in the first day after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

78 people

The number who actually took part.

Started

Jan 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The Patients were assessed the day before surgery in a preoperative visit for evaluation of their medical status, laboratory investigations and for fulfilling all the above inclusion and exclusion criteria. 20g cannula inserted in holding area. Premedication with 0.02 mg/kg midazolam was administered intravenously 5 minutes before block performance.

Ages

21 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age starting from 21 to 60 years. * Genders eligible for study: Male and female sexes. * ASA I-III * Undergoing Laparoscopic bariatric surgery. * BMI \> = 40. Exclusion Criteria: * Patient refusal * Known allergy to local anesthetics and adjuvant drugs used (dexamedatomedine) * Bleeding disorders; platelets count \<50,000, prothrombin concentration \< 60% or any coagulopathy disorder. * Use of any anti-coagulants * Inability to provide informed consent * ASA -IV * Neurological disorders * Patient with psychiatric disorders * Failed block is claimed if the patient required more than 2 doses of rescue analgesia in the first 2 hrs post operative , failed block cases will be recorded , excluded and managed according to the institutional regulations (opioid analgesia).

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Conditions

The condition(s) this trial relates to.

morbid obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Espb with dexmetomidine may provide analgesia

Contacts and locations

Locations

  • Ahmed Abdalla Mohamed

    Cairo, 11451, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.