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New nerve block may cut opioid use after cancer surgery

NCT ID NCT07331129

Symptom relief Sponsor: National Cancer Institute, Egypt Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a nerve block called the transversalis fascia plane block can reduce pain after inguinal lymph node removal in cancer patients. The goal is to lower the need for strong painkillers like opioids, which can cause nausea, dizziness, and breathing problems. 90 adults will be randomly assigned to receive either the nerve block plus local anesthetic or just local anesthetic alone. Pain scores and opioid use will be tracked for 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transversalis fascia plane block (nerve block with local anesthetic)
What this could lead to
If it works, this could offer a better way to manage pain after groin lymph node surgery, reducing the need for opioids and their side effects.
What could go wrong
This is a small, early-phase study (90 people) testing a nerve block that may not work for everyone or could cause rare complications like infection or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. American society of anesthesiologists (ASA) class I and II. 2. Age ≥ 18 and ≤ 65 Years. 3. Cancer patients for inguinal lymph node dissection. 4. Body mass index (BMI): \> 20 kg/m2 and \< 40 kg/m2. Exclusion Criteria: 1. Patient refusal. 2. Local infection at the puncture site. 3. Coagulopathies with platelets count below 50,000 or an INR\>1.6. 4. Unstable cardiovascular disease. 5. History of psychiatric and cognitive disorders. 6. Patients allergic to medication used.

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Conditions

The condition(s) this trial relates to.

cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inguinal lymph nodes enlarged

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • National Cancer Institute Cairo University

    RECRUITING

    Cairo, 11796, Egypt

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