New nerve block may beat morphine for scoliosis surgery pain
NCT ID NCT06820190
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two ways to manage pain after scoliosis surgery: a nerve block called MTP (injected near the spine) versus patient-controlled morphine (PCA). Forty adults with idiopathic scoliosis will be randomly assigned to one of the two methods. The main goal is to see which provides better pain relief in the first 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Morphine (for PCA) and a nerve block (MTP block) using local anesthetic
- What this could lead to
- If the MTP block works better, it could offer a more effective way to manage pain after scoliosis surgery, possibly reducing the need for strong opioids.
- What could go wrong
- This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. The nerve block carries rare risks like infection or bleeding, and it may not prove superior to standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years. * Both sexes. * American Society of Anesthesiology (ASA) physical status I-II. * Idiopathic scoliosis patients undergoing posterior spinal fusion surgery. Exclusion Criteria: * Patients with pre-existing infection at block site. * Known allergy to study drugs. * Coagulation disorder. * History of psychiatric illness. * Pre-existing neurological deficits. * Patient with morbid obesity (body mass index \>40 kg/m2). * Presence of any pre-operative pain or history of chronic pain. * History of regular analgesic.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tanta University
RECRUITINGTanta, El-Gharbia, 31527, Egypt
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Other studies related to the condition(s) this trial covers.
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- Which Anti-Nausea drug wins for scoliosis surgery? a Head-to-Head test
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