Pain pump after liver surgery fails to boost breathing muscle
NCT ID NCT02353702
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving continuous local anesthetic (ropivacaine) near the incision after liver surgery could improve diaphragm function and reduce lung complications. It planned to include 88 adults, but was terminated early after enrolling only 31. The main goal was to measure diaphragm strength using a sniff test. The study was stopped before completion, so results are limited.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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31 people
The number who actually took part.
- Started
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Jul 2014
- Finished
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Jun 2017
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Surgical Indication for Upper abdominal surgery through subcostal incision * More than 18 years old , less than 80 years old * ASA score between 1 and 3 * Effective contraception for more than 3 months in women of childbearing age * Patients signed an informed consent * Affiliation to a social security regimen Exclusion Criteria: * BMI more than 30 kg/m2 * Nasal obstruction during inclusion * Preoperative treatment with morphine * Need for a postoperative nasogastric tube * Difficulty to understand the use of the PCA and/or the sniff-test * Impossibility to place the catheter in preperitoneal position * Pregnant women or breasting women * Patients under guardianship * Contraindication to use of ropivacaine * Inclusion in another clinical trial
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Rouen University Hospital
Rouen, 76031, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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