New study tests better pain relief after belly surgery
NCT ID NCT07593300
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial will test two different nerve blocks (RISS and ESPB) to see which one controls pain better after laparoscopic abdominal surgery. 70 adults having procedures like gallbladder removal or hernia repair will be randomly assigned to receive one of the blocks. Researchers will measure pain levels and how much extra pain medicine is needed over 24 hours.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block (RISS or ESPB)
- What this could lead to
- If one block works better, it could mean less pain and less need for strong painkillers after laparoscopic surgery.
- What could go wrong
- This is a small, early-stage trial (70 people) comparing two procedures. Results may not apply to everyone, and there are always risks like bruising or allergic reaction to the numbing medicine.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients scheduled for laparoscopic abdominal surgery (e.g., cholecystectomy, colectomy, sleeve gastrectomy, hernia repair, appendectomy). * Age from 18 - 60 years old. * Both sexes. * American Society of Anesthesiology (ASA) classification I, II. (i.e., ASA I: a normal healthy patient; ASA II: patients with mild controlled systemic disease. Exclusion Criteria: * Patients who refuse the research consent. * Allergy to local anesthetic drugs. * Cardiac arrhythmia. * Bleeding tendency (including pre-existing blood disease and patients on full anticoagulant therapy). * Morbid obese patients (BMI\>35 kg/m2) * Vascular compromise of lower extremity (e.g., Burger disease, Raynaud's disease). * Connective tissue disease (e.g., Scleroderma). * Suspected malignancy or intra-abdominal infection.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Souad Kafafi University Hospital (SKUH), Faculty of Medicine, MUST
Giza, Giza Governorate, 15525, Egypt
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