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New pain block cocktail could cut opioid use after hip surgery

NCT ID NCT07418671

Symptom relief Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding dexamethasone or magnesium sulfate to a standard numbing drug (bupivacaine) could provide longer pain relief after total hip replacement. 66 adults received an ultrasound-guided nerve block before surgery. The main goal was to see how long it took before patients needed additional pain medicine. The study also tracked total opioid use and pain scores over 24 hours.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

66 people

The number who actually took part.

Started

May 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

22 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Physical status: ASA 1 or 2. * Age \> 21 * Height 160 to 190 cm. * Body Mass Index (BMI) \< 40. Exclusion Criteria: * Refusing to participate in the study. * Coagulopathy. * Patients with history of drug allergies to study drugs. * Inability to cooperate. * Local disease as inflammation or infections at the site of puncture. * Uncontrolled diabetes, significant cardiopulmonary disease, and mental illness.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Erector spinae plane block Post operative pain Total hip arthroplasty (THA)

Contacts and locations

Locations

  • Ain Shams University

    Cairo, Cairo Governorate, 1181, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.