New study aims to find best painkiller for c-section recovery
NCT ID NCT07170267
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compares two ways to manage pain after a C-section: a nerve block (TFP block) and a medication added to spinal anesthesia (intrathecal dexmedetomidine). Fifty women undergoing planned C-sections will be randomly assigned to one of the two methods. Researchers will measure pain levels and how much extra pain medicine is needed over the first 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine and dexmedetomidine
- What this could lead to
- If this trial succeeds, it could point to a better way to manage pain after C-section, reducing the need for strong painkillers like morphine.
- What could go wrong
- This is a small, early-stage study with only 50 participants, so results may not apply to everyone. Both methods have risks like infection or side effects from the medications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age from 18 to 40 years. * American Society of Anesthesiology (ASA) physical status II. * Women undergoing cesarean section under spinal anesthesia. Exclusion Criteria: * Contraindication to spinal anesthesia. * Women with body mass index \>40 kg/m2. * Pregnancy-induced hypertension * Local infection at the site of injection. * Known cardiovascular disease * Coagulation abnormality. * History of chronic pain. * Abuse of drugs or alcohol. * History of allergies to any study medications. * Seizure disorders. * Any pregnancy complications requiring conversion to general anesthesia.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tanta University
RECRUITINGTanta, El-Gharbia, 31527, Egypt
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- Can we predict severe pain after C-Section?