New pain block cocktail could ease surgery recovery
NCT ID NCT07285083
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding dexmedetomidine to the standard painkiller bupivacaine in a nerve block (TAP block) provides better pain relief after abdominal surgery. 80 adults will be randomly assigned to receive either the combo or bupivacaine alone. Pain levels, sedation, and side effects will be tracked for 12 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine with dexmedetomidine
- What this could lead to
- If it works, this could provide better pain control after abdominal surgery with fewer side effects and less need for extra painkillers.
- What could go wrong
- This is a small, early-stage study (80 people) comparing two pain-block methods. The added drug may not improve pain relief or could cause more sedation or side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Aug 2024
- Expected to finish
-
Dec 2025
An estimate. End dates often move.
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
21 to 45 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age between 21 to 45 years. 2. Undergoing elective abdominal surgery (exploratory laparotomy, ileostomy reversal, laparoscopic/open cholecystectomy, mesh repair of paraumbilical hernias). 3. The patient must be capable of providing informed consent. Exclusion Criteria: 1. Pregnancy. 2. Severe allergies to local anesthetics. 3. Pre-existing chronic pain conditions. 4. Participation in another clinical trial within the past 30 days.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Pain, postoperative are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Sheikh Zayed Medical College
RECRUITINGRahim Yar Khan, Punjab Province, 64200, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Three ways to block hernia surgery pain go head to head
- Could a small electrical device cut painkiller use after hip surgery?
- Can a blood pressure drug cut opioid needs during bowel surgery?
- Two nerve blocks go head to head for breast surgery pain
- Propofol vs. inhaled anesthesia: which one spares your recovery?
- A smartphone form may spot hidden post-surgery pain