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Laser vs. gel: which eases orthodontic pain better?

NCT ID NCT07558720

Symptom relief Sponsor: Dow University of Health Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether low-level laser therapy works as well as benzocaine gel for reducing pain when spacers are placed between teeth before braces. 72 people aged 18-25 will receive laser at the dentist and apply gel at home for a week. The goal is to see which method provides better pain relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
low-level laser therapy and 20% benzocaine gel
What this could lead to
If it works, this could offer a non-drug option for managing pain during orthodontic treatment.
What could go wrong
This is a small, early-stage trial with only 72 participants, so results may not apply to everyone. Pain relief from either method may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 72 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 25 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \- Patient aged 18-25 years * no history of previous orthodontic treatment * healthy and complete erupted dentition including permanent second molars * good periodontal health( on basis of periodontal index) * Tight proximal contacts of all permanent first molars (both mesially and distally) Exclusion Criteria: * \- Patients with multiple fillings, root canal treatments, gingivitis,, missing teeth, or spacing between molars and premolars will be excluded from the sample * Severely rotated teeth * posterior open bite * any systematic disease

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pain reduction We are not studying A disease or condition

Contacts and locations

Locations

  • Dow Dental College

    Karachi, Sindh, Pakistan

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