Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can learning about pain change how your body reacts to it?

NCT ID NCT06400329

Knowledge-focused Sponsor: Lisa Carlesso Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two ways of teaching older adults with knee osteoarthritis about their pain. One group learned about the biology of pain and how to manage it, while the other received standard information about joint damage. Researchers measured whether the type of education affected the body's stress response and pain sensitivity. The goal was to see if this kind of study is even possible to run on a larger scale.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Pain Neuroscience Education (PNE) and Standard Pain Education
What this could lead to
If successful, this could show that teaching people about the science of pain helps their nervous system respond better, pointing toward better non-drug approaches for chronic pain.
What could go wrong
This is a small, early feasibility study with only 37 participants, so results may not apply broadly. It measures short-term physiological changes, not long-term pain relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

37 people

The number who actually took part.

Started

Aug 2024

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ≥ 55-85years old * community dwelling adults with a diagnosis of knee osteoarthritis or fulfilling the NICE criteria for knee OA * activity-related joint pain * either no morning joint-related stiffness or morning stiffness that lasts no longer than 30 minutes Exclusion Criteria: * those who have received prior PNE * those who have eye glasses prescription exceeding +/- 6 for spherical correction and/or +3 for astigmatism

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Chronic pain are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pain Osteoarthritis

Contacts and locations

Locations

  • McMaster University

    Hamilton, Ontario, L8S1C7, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.