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Pain education may ease carpal tunnel without surgery

NCT ID NCT07302282

Symptom relief Sponsor: Karamanoğlu Mehmetbey University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times

Summary

This study tests whether pain neuroscience education (PNE) can improve symptoms in people with mild to moderate carpal tunnel syndrome. Participants will receive PNE along with standard home exercises and a wrist splint. The goal is to see if understanding pain better leads to less pain and better hand function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
pain neuroscience education
What this could lead to
If it works, this could offer a simple, non-drug way to ease pain and numbness in people with mild to moderate carpal tunnel syndrome.
What could go wrong
This is a small, early-stage trial with only 48 participants. The education may not provide significant benefit beyond standard exercises and splints.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

48 people

The number who actually took part.

Started

Dec 2025

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being 18 years of age or older * Having a diagnosis of mild or moderate CTS confirmed by ENMG * Having complaints of pain and numbness in the first three fingers of the hand for at least 3 months Exclusion Criteria: * Presence of severe CTS findings on electrophysiological examination * Presence of metabolic diseases such as uncontrolled diabetes and hypothyroidism * Presence of inflammatory rheumatic disease (e.g., rheumatoid arthritis) * Presence of other neuromuscular diseases affecting the hand and wrist (Polyneuropathy, Cervical radiculopathy, peripheral nerve damage, Brachial plexus damage, other entrapment neuropathies, etc.) * History of hand and wrist trauma * History of neck and wrist surgery * History of steroid injection into the carpal tunnel within the last 3 months * History of physical therapy application to wrist within the last 3 months * Deformity preventing the use of a splint on the wrist * Previous participation in a program for the psychological management of chronic pain * Cognitive dysfunction preventing cooperation with tests

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome median nerve neuropathy mononeuropathy Motor Activity nerve compression syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carpal tunnel syndrome (CTS)

Contacts and locations

Locations

  • Karaman Training and Research Hospital

    Karaman, Karaman, 70200, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.