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New pain block technique tested for heart surgery recovery

NCT ID NCT05320718

Symptom relief Sponsor: Peking University Third Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This study compared two ways to control pain after minimally invasive heart bypass surgery: a newer erector spinae plane block (ESPB) versus the standard paravertebral block (PVB). 140 patients received one of the two blocks using the numbing drug ropivacaine. The goal was to see if ESPB works as well as PVB for pain relief, especially when coughing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ropivacaine
What this could lead to
If successful, this could show that a newer, simpler nerve block (ESPB) is just as good as the standard one (PVB) for controlling pain after heart surgery.
What could go wrong
This is a small, completed study comparing two established techniques. The results may not apply to all heart surgeries or patients, and both blocks carry risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

140 people

The number who actually took part.

Started

Apr 2022

Finished

Dec 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients undergoing elective minimally invasive direct coronary artery bypass grafting Exclusion Criteria: 1. Contraindications to regional anesthesia (coagulopathy, infection of the skin at the site of needle puncture area, et al) 2. Morbid obesity (body mass index \> 35 kg/m2) 3. Allergy to any of the study drugs 4. Chronic opioid use or history of opioid abuse. 5. Inability to understand pain score

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia, local Regional anesthesia Surgery

Contacts and locations

Locations

  • Department of Anesthesiology,Peking University Third Hospital

    Beijing, Beijing Municipality, 100191, China

  • Peking University Third Hosptial

    Beijing, 100191, China

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