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Which nerve block combo best eases pain after gynecologic cancer surgery?

NCT ID NCT07312825

Knowledge-focused Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 94 patients who had major abdominal surgery for gynecologic cancers. Researchers compared pain relief from a standard nerve block (TAP block) alone versus combining it with another block (QLB or RSB). The goal was to see which approach reduced pain and opioid use after surgery. All blocks were given as part of routine care, not assigned by the study.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nerve blocks (TAP block, Quadratus Lumborum block, Rectus Sheath block)
What this could lead to
If it works, this could point toward a better way to manage pain after gynecologic cancer surgery, possibly reducing opioid use and speeding recovery.
What could go wrong
This is an observational study, not a randomized trial, so results may be influenced by patient differences. It is also small (94 patients) and completed, so findings need confirmation in larger trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

94 people

The number who actually took part.

Started

Jan 2024

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult female patients who are undergoing elective major abdominal surgery due to gynecologic cancer (e.g., endometrial cancer, ovarian cancer, debulking surgery). Participants will be aged 18 years and older, and only those with ASA I-IV status who are deemed fit for surgery will be included.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Age 18 years or older. * ASA physical status I-IV. * Scheduled for major gynecologic oncology surgery (endometrial cancer, ovarian tumor, or cytoreductive surgery). * Undergoing general anesthesia. * Planned postoperative abdominal fascial plane block for pain management (TAP, TAP + QLB, or TAP + RSB). * Able to provide written informed consent. Exclusion Criteria * Refusal to participate or inability to provide informed consent. * Emergency surgery. * Known allergy or contraindication to local anesthetics. * Infection at the block site. * Coagulopathy or anticoagulant use that contraindicates regional anesthesia. * Pre-existing chronic pain conditions or chronic opioid use. * Severe hepatic or renal insufficiency. * Cognitive impairment that prevents reliable pain assessment.

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Conditions

The condition(s) this trial relates to.

endometrial cancer female reproductive organ cancer ovarian neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gynecologic cancers Postoperative pain management

Contacts and locations

Locations

  • Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital

    Ankara, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.