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New pain block could cut opioid use after heart surgery

NCT ID NCT07259824

First seen Dec 15, 2025 · Last updated Jun 22, 2026 · Updated 21 times

Summary

This study tested whether a special nerve block, called the serratus posterior superior intercostal plane block, can reduce pain and the need for strong painkillers after minimally invasive heart surgery. Fifty adults were randomly assigned to receive either the nerve block plus standard care or standard care alone. Researchers measured total opioid use in the first 24 hours after surgery, along with pain scores and recovery speed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    Ankara, 06800, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bupivacaine

What this could lead to

If effective, this nerve block could become a standard way to reduce pain and opioid use after minimally invasive heart surgery, helping patients recover more comfortably.

What could go wrong

This is a small, single-center study with only 50 participants. The results may not apply to all patients or surgeries, and the block carries small risks like bleeding or infection.

Conditions

The condition(s) this trial relates to.

heart valve disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.