New study aims to find best pain block for kidney surgery recovery
NCT ID NCT07556536
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two ultrasound-guided nerve blocks—serratus intercostal plane block and erector spinae plane block—for pain control after open kidney removal. 132 adults scheduled for elective open nephrectomy will be randomly assigned to receive one of the two blocks. The goal is to see which block provides better pain relief and reduces the need for opioids, helping patients recover faster with fewer side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine (a local anesthetic)
- What this could lead to
- If one block works better, it could offer a safer, more effective way to manage pain after kidney surgery, reducing opioid use and speeding recovery.
- What could go wrong
- This is a small, early-stage comparison study, not a large confirmatory trial. Results may not apply to all patients or surgeries, and individual responses to nerve blocks vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 132 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients scheduled for elective open nephrectomy under general anesthesia via flank incision . 2. Adult patients aged 18-65 years. 3. Patients with an American Society of Anesthesiologists (ASA) physical status I to III. Exclusion Criteria: 1. Patient refusal. 2. Allergy to local anesthetics and patient with infection at the injection site of block. 3. Coagulation disorders or ongoing anticoagulant therapy. 4. Patients receiving opioids for chronic analgesic therapy (cancer, addiction). 5. Cognitive impairment preventing pain scoring. 6. Neurological or psychiatric disorders affecting pain assessment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Fayoum university hospital
RECRUITINGAl Fayyum, 084, Egypt
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- One pill before surgery may cut opioid use and improve sleep