New study aims to ease hysterectomy pain without opioids
NCT ID NCT07480499
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of nerve blocks—erector spinae plane block and quadratus lumborum block—to see which provides better pain relief after total abdominal hysterectomy. Sixty women aged 35-60 will receive one of the blocks with a numbing medicine. The goal is to reduce pain and the need for opioid drugs, which can cause side effects like nausea and drowsiness.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If one block works better, it could mean less pain and fewer opioid side effects after hysterectomy.
- What could go wrong
- This is a small, early-stage trial with only 60 participants. Results may not apply to everyone, and neither block may prove clearly superior.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients aged 35-60 years. ASA physical status I or II. Elective Total Abdominal Hysterectomy under General Anesthesia. Exclusion Criteria: Allergy with local anesthetics. Infection in the injection site. Coagulopathy or anticoagulant use. Morbid obesity (BMI \> 35 kg/m²).
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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SKBZN CMH Muzaffarabad
Muzaffarabad, Azad Kashmir, 13100, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can adding tramadol to spinal anesthesia extend pain relief after leg surgery?
- Spinal block showdown: can one injection method beat another for Post-Surgery pain?
- Could a muscle relaxant speed up recovery after pelvic surgery?
- Can a laser beam replace opioids for knee surgery pain?
- Can skipping opioids during surgery improve recovery?
- Can a safer nerve block match the gold standard for Post-Mastectomy pain?