New study seeks best pain relief for hip replacement patients
NCT ID NCT07667231
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of nerve blocks used to manage pain after total hip replacement. Sixty adults having hip replacement will receive either a quadro-iliac plane block or a PENG block combined with a lateral femoral cutaneous nerve block. Researchers will measure pain scores, opioid use, and how quickly patients can walk after surgery to see which method works better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If one block proves better, it could lead to less pain and faster recovery after hip replacement surgery.
- What could go wrong
- This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. Both blocks are already used, so no major breakthrough is expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 18 and 80 years * American Society of Anesthesiologists physical status I-III * Scheduled for elective unilateral primary total hip arthroplasty * Surgery planned under spinal anesthesia * Ability to understand and use the Numeric Rating Scale * Written informed consent provided Exclusion Criteria: * Refusal to participate * Revision total hip arthroplasty * Bilateral total hip arthroplasty * Contraindication to spinal anesthesia * Contraindication to peripheral nerve block * Known allergy to local anesthetics or study drugs * Coagulopathy or anticoagulant use incompatible with neuraxial/regional anesthesia * Infection at the block injection site * Pre-existing neurological deficit involving the operative lower extremity * Peripheral neuropathy * Chronic opioid use * Cognitive impairment or inability to communicate reliably * Severe hepatic or renal failure * Body mass index \>35 kg/m² * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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