Nerve block showdown: which injection eases gallbladder surgery pain best?
NCT ID NCT07655323
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests two types of nerve blocks—erector spinae plane block and rhomboid intercostal-subserratus plane block—for pain after laparoscopic gallbladder removal. About 80 adults having elective surgery will receive one of the blocks before the procedure. Researchers will measure pain scores, opioid use, and how well the diaphragm works to see which block offers better pain control and recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block (local anesthetic injection)
- What this could lead to
- If one block works better, it could reduce opioid use and improve recovery after gallbladder surgery.
- What could go wrong
- This is a small, early-stage trial. Results may not apply to all patients, and nerve blocks carry rare risks like infection or allergic reaction.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria:- * Age between 18 and 75 years * ASA physical status I-III * Scheduled for elective laparoscopic cholecystectomy under general anesthesia * Provision of written informed consent Exclusion Criteria: * Coagulation disorders or anticoagulant therapy * Known allergy to local anesthetics * Infection at the block application site * Pregnancy or lactation * Chronic opioid use * Cognitive impairment * Refusal to participate in the study * Technical inability to perform the block * Failed block
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Bursa City Hospital
RECRUITINGBursa, Nilüfer, 16100, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a common anesthetic stop Post-Surgery delirium in the elderly?
- Can a single drug dose curb opioid side effects after kidney stone surgery?
- Can a new Non-Opioid pill cut painkiller needs after throat surgery?
- Can zapping three acupoints rewire the brain to ease surgical pain?
- Can a triage checklist ease pain months after emergency surgery?
- Can a nerve block quiet the brain during gallbladder surgery?